1 3-diacetylindole CAS 17537-64-3
Product Name: 1 3-diacetylindole
CAS: 17537-64-3
MF: C12H11NO2
MW: 201.22
EINECS: 241-532-5
Melting point: 144-147°C
Boiling point: 338.8±15.0 °C
Density: 1.16±0.1 g/cm3
Storage temp.: Inert atmosphere,Room Temperature
1. 1,3-Diacetylindole CAS 17537-64-3 is a key heterocyclic building block used in synthetic and medicinal chemistry as a versatile precursor for developing more complex, biologically active molecules .
2. 1,3-Diacetylindole is employed in the synthesis of compounds with antimicrobial, antioxidant, and potential HIV-1 integrase inhibitory activities .
3. The 1,3-diacetylation pattern of 1,3-Diacetylindole enables chemoselective deprotection strategies, where the N1-acetyl group can be selectively removed under mild conditions while the C3-acetyl group remains intact, offering orthogonal protection in multi-step syntheses .
Packed in 1 kg/bag, 25 kg/drum
1. 1,3-Diacetylindole is harmful if swallowed and is classified as an irritant (Xi) . It is also harmful by inhalation and in contact with skin .
2. When handling 1,3-Diacetylindole, wear suitable personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Use only in a chemical fume hood .
3. In case of eye or skin contact, rinse immediately with copious amounts of water for at least 15 minutes and seek medical attention if irritation persists. If inhaled, remove to fresh air .
1. Isolate the spill area of 1,3-Diacetylindole, ensure adequate ventilation, and wear full personal protective equipment including gloves, safety goggles, and a dust mask .
2. Avoid generating dust from 1,3-Diacetylindole; mix the spilled material with sand or similar inert absorbent, sweep up carefully, and place into a sealed, suitable container for disposal .
3. Prevent 1,3-Diacetylindole from entering drains or waterways, and dispose of all collected waste in accordance with local environmental regulations .
1. Store 1,3-Diacetylindole CAS 17537-64-3 in closed vessels in a cool, dry place, preferably under inert atmosphere and protected from moisture, as it is moisture sensitive .
2. Keep 1,3-Diacetylindole away from heat, sparks, open flames, and oxidizing agents to prevent hazardous reactions .
3. Store 1,3-Diacetylindole at room temperature under inert atmosphere for optimal stability .
