1-Methylindole CAS 603-76-9
Product Name: 1-Methylindole
CAS: 603-76-9
MF: C9H9N
MW: 131.17
EINECS: 210-057-5
Melting point: 61.2°C
Boiling point: 133 °C
Density: 1.051 g/mL
Refractive index: n20/D 1.606
Fp: >230 °F
Storage temp.: Keep in dark place,Sealed in dry,Room Temperature
1. 1-Methylindole CAS 603-76-9 is a key reactant in the synthesis of pharmaceutically active compounds, including 2-oxo-1-pyrrolidine analogues, anticancer agents, and Src kinase inhibitors.
2. 1-Methylindole serves as a precursor for preparing positron emission tomography imaging agents targeting protein kinase C and glycogen synthase kinase-3.
3. 1-Methylindole is used in electrochemical synthesis due to its controlled oxidation potential, which helps prevent unwanted polymerization, and as a key intermediate in the synthesis of the drug Osimertinib.
Packed in 1 kg/bottle, 25 kg/drum
1. 1-Methylindole CAS 603-76-9 causes skin irritation and serious eye irritation; it may also cause respiratory irritation.
2. When handling 1-Methylindole, avoid breathing vapors and wear protective gloves, eye/face protection, and appropriate clothing.
3. 1-Methylindole has a strong unpleasant odor (stench) and is light-sensitive; in case of eye contact, rinse cautiously with water for several minutes and seek medical attention.
1. Isolate the spill area of 1-Methylindole, ensure adequate ventilation, and wear full personal protective equipment including gloves, safety goggles, and protective clothing.
2. Absorb the spill of 1-Methylindole with an inert absorbent material such as sand or universal binder, then place it into a sealed, suitable container for disposal.
3. Prevent 1-Methylindole from entering drains or waterways, and dispose of all collected waste in accordance with local environmental regulations.
1. Store 1-Methylindole in a tightly sealed container in a cool, dark place (recommended below 15°C) under inert gas, as it is light- and air-sensitive.
2. For long-term storage, keep the pure compound at -20°C (stable for up to 3 years) or at 4°C (stable for up to 2 years); stock solutions can be stored at -80°C for up to 6 months or at -20°C for up to 1 month.
3. Keep 1-Methylindole away from strong oxidizing agents, as they are incompatible.
