4-chloro-7-azaindole CAS 55052-28-3
Product Name: 4-Chloro-7-azaindole
CAS: 55052-28-3
MF: C7H5ClN2
MW: 152.58
EINECS: 626-806-8
Melting point: 176-181 °C
Density: 1.425±0.06 g/cm3
Storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
1. 4-Chloro-7-azaindole is a key heterocyclic building block used as a privileged scaffold in medicinal chemistry, particularly for designing kinase inhibitors, due to its ability to mimic purine bases and form hydrogen bonds with the ATP-binding site.
2. 4-Chloro-7-azaindole serves as a versatile intermediate in the synthesis of JAK family inhibitors for autoimmune and inflammatory diseases, and it is used to create metal-based anticancer agents.
3. 4-Chloro-7-azaindole is employed as a biochemical reagent for life science research and as a sulfonylation reagent in organic synthesis and drug discovery.
Packed in 1 kg/bag, 25 kg/drum
1. 4-Chloro-7-azaindole is toxic if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation.
2. When handling 4-Chloro-7-azaindole, avoid breathing dust and wear protective gloves, eye/face protection, and appropriate protective clothing.
3. In case of eye contact with 4-Chloro-7-azaindole, rinse cautiously with water for several minutes, remove contact lenses if present, and continue rinsing. Immediately seek medical attention.
1. Isolate the spill area of 4-Chloro-7-azaindole, ensure adequate ventilation, and wear full personal protective equipment including gloves, safety goggles, and a dust mask.
2. Avoid generating dust from 4-Chloro-7-azaindole; carefully sweep up or vacuum the spilled material and place 4-Chloro-7-azaindole into a sealed, suitable container for disposal.
3. Prevent 4-Chloro-7-azaindole from entering drains or waterways, and dispose of all collected waste in accordance with local environmental regulations.
1. Store 4-Chloro-7-azaindole powder at -20°C for long-term stability up to 3 years, or at 4°C for up to 2 years.
2. For 4-Chloro-7-azaindole stock solutions, store at -80°C for up to 6 months or at -20°C for up to 1 month.
3. Keep 4-Chloro-7-azaindole in a tightly sealed container in a cool, dry, well-ventilated place, away from oxidizing agents and protected from light.
