5-Benzylthio-1H-tetrazole CAS 21871-47-6
Product Name: 5-Benzylthio-1H-tetrazole
CAS: 21871-47-6
MF: C8H8N4S
MW: 192.24
EINECS: 606-853-0
Density: 1.38 g/cm3
Melting point: 135-138°C
Boiling point: 389.3±35.0 °C
Refractive index: n20/D 1.354
Fp: 2 °C
Storage temp.: -20°C Freezer, Under inert atmosphere
1. 5-Benzylthio-1H-tetrazole is primarily used as a highly effective activator in the synthesis of oligonucleotides, where it activates phosphoramidite groups to form internucleotide bonds.
2. 5-Benzylthio-1H-tetrazole serves as a versatile building block in pharmaceutical development, particularly for creating compounds with anti-inflammatory, analgesic, and antimicrobial activities.
3. 5-Benzylthio-1H-tetrazole is also applied in agricultural chemistry as a precursor for agrochemicals and in material science for preparing organosilicon compounds with antibacterial activity.
Packed in 1kg/bag, 25kg/drum
1. 5-Benzylthio-1H-tetrazole causes skin irritation, serious eye damage, and may cause respiratory irritation.
2. 5-Benzylthio-1H-tetrazole is harmful if swallowed, in contact with skin, or if inhaled, requiring immediate medical attention for eye contact.
3. Wear appropriate personal protective equipment including protective gloves, eye/face protection, and work in a well-ventilated area. In case of eye contact, rinse cautiously with water for several minutes and seek immediate medical attention.
1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including dust mask, gloves, and eyeshields before attempting cleanup.
2. Avoid generating dust; carefully sweep or vacuum the spilled material with spark-proof tools and place it into a sealed, suitable container for disposal.
3. Prevent the material from entering drains or waterways, and dispose of all collected waste in accordance with local environmental regulations.
1. Store 5-Benzylthio-1H-tetrazole in a tightly sealed, light-protected container at a temperature of 2-10°C (refrigerated), preferably under an inert gas atmosphere to prevent degradation.
2. Keep 5-Benzylthio-1H-tetrazole away from strong oxidizing agents, as the product may contain residual toluene (up to 5%) which has established exposure limits.
3. Handle 5-Benzylthio-1H-tetrazole with care to minimize dust generation, as it is a combustible solid requiring dust mask, eyeshields, and gloves for personal protection.
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