5-Flluoroisatin CAS 443-69-6
Product Name: 5-Fluoroisatin
CAS: 443-69-6
MF: C8H4FNO2
MW: 165.12
EINECS: 628-890-1
Melting point: 224-227 °C (lit.)
Density: 1.477±0.06 g/cm3(Predicted)
Storage temp.: Sealed in dry,Room Temperature
1. 5-Fluoroisatin CAS 443-69-6 is a key intermediate in pharmaceutical synthesis, used to develop anticancer, antiviral, and antibacterial drugs—its fluorinated isatin scaffold enables targeted binding to biological targets, while 5-Fluoroisatin cyclic ketone and amide groups support versatile reactions to build bioactive molecules.
2. 5-Fluoroisatin serves as a building block in organic synthesis research, aiding the creation of complex heterocyclic compounds (e.g., indoles, quinazolines) through ring-opening or cyclization reactions, 5-Fluoroisatin CAS 443-69-6 are vital for testing new chemical entities.
3. 5-Fluoroisatin finds application in medicinal chemistry studies, supporting the design of enzyme inhibitors (e.g., for kinases or proteases), as the fluorine substituent enhances metabolic stability and potency of potential therapeutic agents.
Packed in 25 kg per drum or based on customers' requirements.
1. Always wear appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles, and a lab coat, when handling 5-Fluoroisatin—its solid form may cause skin/eye irritation, and inhalation of fine particles can irritate the respiratory tract.
2. Work in a well-ventilated fume hood, especially when weighing or transferring the compound, to minimize exposure to airborne dust; avoid direct contact with skin, and do not eat, drink, or smoke in the handling area to prevent accidental ingestion.
3. In case of accidental exposure: rinse skin with plenty of water for 15+ minutes, flush eyes with water for 15+ minutes (and seek medical help if irritation persists), and move to fresh air if inhaled—also, dispose of contaminated PPE or waste per local hazardous chemical regulations.
1. Store 5-Fluoroisatin CAS 443-69-6 in a tightly sealed, light-resistant container to protect it from light and moisture—its isatin structure and fluorine substituent may be sensitive to photodegradation or hydrolysis, 5-Fluoroisatin can reduce purity.
2. Keep 5-Fluoroisatin in a cool, dry area away from direct sunlight and heat sources; elevated temperatures could accelerate decomposition of its cyclic amide-ketone scaffold over time.
3. Avoid storing 5-Fluoroisatin CAS 443-69-6 near strong oxidizers, acids, or bases to prevent unwanted reactions (e.g., ring-opening or substitution of the fluorine group) that might compromise the compound’s stability and usability.
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