6-cyano-7-azaindole CAS 189882-33-5
Product Name: 6-cyano-7-azaindole
CAS: 189882-33-5
MF: C8H5N3
MW: 143.15
EINECS: 251-156-6
Melting point: 187.4 °C
Boiling point: 463.9±28.0 °C
Density: 1.29±0.1 g/cm3
Storage temp.: 2-8°C
1. 6-Cyano-7-azaindole is primarily used as a key synthetic intermediate in medicinal chemistry, particularly for the development of selective kinase inhibitors, including cyclin-dependent kinase 7 (CDK7) inhibitors.
2. 6-Cyano-7-azaindole serves as a versatile building block for creating pharmacologically active compounds through various functionalization reactions, such as Grignard additions.
3. 6-Cyano-7-azaindole has been investigated for its biological activity, including antitumor and kinase inhibition properties, making it valuable in oncology research.
Packed in 1 kg/bag, 25 kg/drum
1. 6-Cyano-7-azaindole is harmful if swallowed and causes skin, eye, and respiratory tract irritation.
2. When handling 6-Cyano-7-azaindole, avoid breathing dust and wear protective gloves, eye/face protection, and appropriate clothing.
3. Work in a well-ventilated area or fume hood. In case of eye contact, rinse cautiously with water for several minutes and seek medical attention if irritation persists.
1. Isolate the spill area of 6-Cyano-7-azaindole, ensure adequate ventilation, and wear full personal protective equipment including gloves, safety goggles, and a dust mask.
2. Avoid generating dust from 6-Cyano-7-azaindole; carefully sweep up or vacuum the spilled material and place it into a sealed, suitable container for disposal.
3. Prevent 6-Cyano-7-azaindole from entering drains or waterways, and dispose of all collected waste in accordance with local environmental regulations.
1. Store 6-Cyano-7-azaindole in a tightly sealed container in a cool, dry, and well-ventilated place, protected from light, as it is air-sensitive.
2. For long-term storage, keeping 6-Cyano-7-azaindole at -20°C is recommended to maintain stability.
3. Keep 6-Cyano-7-azaindole away from strong oxidizing agents and sources of ignition.