Dimethyl itaconate CAS 617-52-7
Product Name: Dimethyl itaconate
CAS: 617-52-7
MF: C7H10O4
MW: 158.15
EINECS: 210-519-6
Density: 1.124 g/mL
Melting point: 37-41 °C
Boiling point: 208 °C
1. Dimethyl itaconate CAS 617-52-7 is primarily used as an immunomodulatory research tool to study trained immunity, anti-inflammatory responses, and Nrf2 activation in cellular and animal models .
2. Dimethyl itaconate serves as a chemical reagent in organic synthesis for copolymerization, functionalization of polypropylene, and crosslinking of polyesters .
3. Dimethyl itaconate is utilized in fragment-based drug discovery as a building block for synthesizing functionalized compounds such as 2-isoxazolines .
Packed in 25kg/drum.
1. Dimethyl itaconate CAS 617-52-7 is a synthetic organic compound produced by esterification of itaconic acid with methanol, using lipase catalysts or chemical methods .
2. Dimethyl itaconate can be produced bio-based from renewable resources such as rice wine waste-derived itaconic acid using engineered Corynebacterium glutamicum strains .
3. Dimethyl itaconate is commercially manufactured by chemical synthesis and available from major suppliers including Sigma-Aldrich, Thermo Fisher, and BOC Sciences .
1. Dimethyl itaconate is classified as harmful if swallowed and is a moderate to severe irritant to skin and eyes, requiring handling only by trained personnel .
2. Dimethyl itaconate contains a pharmaceutically active ingredient, and handling should be performed with chemical-resistant gloves, safety goggles, and NIOSH-approved respirators .
3. Dimethyl itaconate may pose risks of impaired fertility and possible harm to the unborn child according to EU risk phrases .
1. Store Dimethyl itaconate in a tightly closed container in a cool, dry, well-ventilated area away from incompatible substances .
2. Store Dimethyl itaconate away from strong oxidizing agents, protect from light and heat, as thermal decomposition may produce toxic gases including carbon monoxide .
3. For long-term storage, keep Dimethyl itaconate container closed when not in use and store as a combustible solid.
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