Ethyl indole-2-carboxylate CAS 3770-50-1
Product Name: Ethyl indole-2-carboxylate
CAS: 3770-50-1
MF: C11H11NO2
MW: 189.21
EINECS: 223-206-4
Melting point: 122-125 °C
Boiling point: 324.47°C
Density: 1.1596 g/cm3
Refractive index: n20/D 1.5012
Storage temp.: Keep in dark place,Sealed in dry,Room Temperature
1. Ethyl indole-2-carboxylate is a key reactant for preparing CRTH2 receptor antagonists, indoleamine 2,3-dioxygenase (IDO) inhibitors, and cannabinoid CB1 receptor antagonists .
2. Ethyl indole-2-carboxylate is used in the synthesis of inhibitors of human reticulocyte 15-lipoxygenase-1 and acetolactate synthase inhibitors .
3. Ethyl indole-2-carboxylate serves as a versatile substrate in the Mannich reaction, enabling the synthesis of 3-aminomethyl indole derivatives with antimicrobial and cytotoxic activities .
Packed in 1 kg/bag, 25 kg/drum
1. Ethyl indole-2-carboxylate causes skin irritation and serious eye irritation .
2. When handling Ethyl indole-2-carboxylate, wear protective gloves and eye/face protection, and wash thoroughly after handling .
3. In case of eye contact, rinse cautiously with water for several minutes and remove contact lenses if present; if eye irritation persists, get medical advice .
1. Isolate the spill area of Ethyl indole-2-carboxylate, ensure adequate ventilation, and wear full personal protective equipment including gloves, safety goggles, and a dust mask.
2. Avoid generating dust from Ethyl indole-2-carboxylate; carefully sweep up or vacuum the spilled material and place it into a sealed, suitable container for disposal.
3. Prevent Ethyl indole-2-carboxylate from entering drains or waterways, and dispose of all collected waste in accordance with local environmental regulations.
1. Store Ethyl indole-2-carboxylate in a tightly closed container in a cool, dry, well-ventilated area away from incompatible substances .
2. For stock solutions, store Ethyl indole-2-carboxylate at -80°C for up to 6 months or at -20°C for up to 1 month .
3. Store Ethyl indole-2-carboxylate at room temperature below 15°C in a dark, dry place .
