Glimepiride CAS 93479-97-1
Product Name: Glimepiride
CAS: 93479-97-1
EINECS: 642-919-5
Melting point: 212.2-214.5 °C
Density: 1.29±0.1 g/cm3
1. Glimepiride is used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
2. Glimepiride is not for treating type 1 diabetes mellitus or diabetic ketoacidosis, as Glimepiride would not be effective in these settings.
3. Glimepiride works primarily by stimulating the release of insulin from functioning pancreatic beta cells and may also increase peripheral tissue sensitivity to insulin.
Packed in 1kg/bag, 25kg/drum
1. Glimepiride is a synthetic sulfonylurea compound with the molecular formula C24H34N4O5S, identified chemically as 1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea.
2. Glimepiride can be synthesized starting from ethyl acetoacetate through an eight-step reaction process, with raw materials that are readily available and reaction conditions suitable for industrial production.
3. Glimepiride is manufactured as tablets in various strengths (1 mg, 2 mg, 3 mg, 4 mg, and 8 mg) and is available as a prescription drug from multiple pharmaceutical manufacturers globall.
1. If hypoglycemia occurs (symptoms include dizziness, sweating, confusion, headache), immediately consume a fast-acting source of glucose such as fruit juice, hard candy, or glucose tablets.
2. If the person is unconscious or unable to swallow due to severe hypoglycemia, do not give anything by mouth and seek emergency medical attention immediately.
3. If an allergic reaction (rash, itching, swelling, difficulty breathing) is suspected, promptly discontinue Glimepiride and seek immediate medical attention.
1. Store Glimepiride tablets in well-closed containers at a temperature not exceeding 25°C.
2. For Glimepiride powder, store at room temperature in a tightly closed container, protected from light, moisture, and kept in a dry place.
3. USP monograph specifies that assay preparations of Glimepiride should be kept at a temperature not exceeding 12°C and stored no longer than 15 hours.
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