P-Toluenesulfonic Anhydride CAS 4124-41-8
Product Name: P-Toluenesulfonic anhydride
CAS: 4124-41-8
MF: C14H14O5S2
MW: 326.38
EINECS: 223-926-9
Melting point: 121-127 °C(lit.)
Boiling point: 478.0±48.0 °C(Predicted)
Density: 1.361±0.06 g/cm3(Predicted)
Storage temp.: Inert atmosphere,2-8°C
1. p-Toluenesulfonic Anhydride is primarily used as a powerful reagent in synthetic organic chemistry for the synthesis of sulfonamides and other sulfonate esters, making p-Toluenesulfonic Anhydride essential for developing pharmaceuticals and agrochemicals .
2. p-Toluenesulfonic Anhydride CAS 4124-41-8 acts as a derivatizing agent in analytical chemistry for the analysis of alcohols and amines, improving detection sensitivity in chromatographic techniques .
3. p-Toluenesulfonic Anhydride is utilized in polymer chemistry as a catalyst for polymerization reactions and in electronics manufacturing for producing photoresists in semiconductor fabrication .
Packed in 25 kg per drum or based on customers' requirements.
1. p-Toluenesulfonic Anhydride is a synthetic organic compound produced by the dehydration of p-toluenesulfonic acid using reagents such as phosphorus pentoxide or thionyl chloride .
2. In a typical synthesis method, p-toluenesulfonic acid CAS 4124-41-8 monohydrate is reacted with thionyl chloride in a solvent like methylcyclohexane at elevated temperatures (50-76°C) to yield p-Toluenesulfonic Anhydride .
3. p-Toluenesulfonic Anhydride can also be prepared using phosphorus pentoxide with inert materials like kieselguhr and asbestos, followed by extraction with ethylene chloride and purification by recrystallization from benzene and ether .
1. p-Toluenesulfonic Anhydride is classified as a dangerous substance with the signal word "Danger" and causes severe skin burns and eye damage (H314) according to GHS hazard classifications .
2. p-Toluenesulfonic Anhydride CAS 4124-41-8 may be corrosive to metals (H290), and when handling p-Toluenesulfonic Anhydride, workers must wear protective gloves, protective clothing, eye protection, and face protection .
3. If p-Toluenesulfonic Anhydride gets on skin or in eyes, rinse cautiously with water for several minutes and immediately call a poison center or doctor, and wash contaminated clothing before reuse .
1. Store p-Toluenesulfonic Anhydride in a cool, dark, and dry place at temperatures below 15°C (59°F), with some suppliers specifically recommending storage at -20°C .
2. Store p-Toluenesulfonic Anhydride CAS 4124-41-8 under inert gas in a tightly closed container, keeping p-Toluenesulfonic Anhydride away from moisture as p-Toluenesulfonic Anhydride is moisture sensitive .
3. Store p-Toluenesulfonic Anhydride in a corrosive-resistant container with a resistant inner liner, and store p-Toluenesulfonic Anhydride locked up in a well-ventilated area .
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