Procaine hydrochloride CAS 51-05-8
Product Name: Procaine hydrochloride
CAS: 51-05-8
MF: C13H21ClN2O2
MW: 272.77
EINECS: 200-077-2
Melting point: 155-156 °C(lit.)
Boiling point: 195-196°C 17mm
Density: 1.1761 (rough estimate)
Refractive index: 1.5270 (estimate)
Fp: 195-196°C/17mm
Storage temp.: 2-8°C
1. Procaine hydrochloride is primarily used as a short-acting local anesthetic of the ester type for local infiltration, peripheral nerve block, and spinal block .
2. Procaine hydrochloride CAS 51-05-8 is also used in intravenous combined anesthesia and as a raw material for preparing penicillin procaine .
3. Procaine hydrochloride lacks topical anesthetic activity due to its poor penetration through skin and mucous membranes .
Packed in 25 kg per drum or based on customers' requirements.
1. Procaine hydrochloride is a synthetic organic compound produced via chemical synthesis, with the CAS Registry Number 51-05-8 and molecular formula C13H20N2O2·HCl .
2. Procaine hydrochloride CAS 51-05-8 is manufactured by esterifying p-nitrobenzoic acid with diethylaminoethanol, followed by catalytic hydrogenation to reduce the nitro group to an amino group .
3. Procaine hydrochloride is commercially produced using methods such as direct esterification or indirect esterification with butanol as a water-carrying agent, followed by purification through crystallization and filtration .
1. Procaine hydrochloride can cause central nervous system reactions ranging from restlessness, tremors, and convulsions to depression and respiratory arrest at toxic blood concentrations .
2. Procaine hydrochloride CAS 51-05-8 may cause allergic reactions including rash, urticaria, and in rare cases anaphylaxis, particularly in patients sensitive to para-aminobenzoic acid (PABA) or its derivatives .
3. Procaine hydrochloride requires immediate availability of resuscitative equipment, oxygen, and trained personnel when administered, as delayed management of toxicity can lead to acidosis and cardiac arrest .
1. Store Procaine hydrochloride in a well-closed, light-resistant container away from light and heat to maintain stability .
2. For Procaine hydrochloride CAS 51-05-8 powder, storage at -20°C for up to 3 years or at 4°C for up to 2 years is recommended .
3. For Procaine hydrochloride stock solutions in solvent, storage at -80°C for up to 6 months or at -20°C for up to 1 month is recommended, avoiding repeated freeze-thaw cycles .
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