Tosyl azide CAS 941-55-9
Product Name: Tosyl azide
CAS: 941-55-9
MF: C7H7N3O2S
MW: 197.21
EINECS: 213-381-5
Melting point: 22 °C
Density: ~0.90 g/mL
Refractive index: n20/D 1.548
Fp: 4℃
Storage temp.: 2-8°C
1. Tosyl azide is widely used as a diazo-transfer reagent to introduce diazo functional groups onto active methylene positions, often yielding high product yields under mild conditions.
2. Tosyl azide serves as a nitrene source and participates in [3+2] cycloaddition reactions to form triazoles and aziridines, making it valuable in synthetic and medicinal chemistry.
3. Tosyl azide is utilized in the synthesis of N-sulfonylamidines and as a modifier in polymer chemistry for applications such as creating permanent patterns in PMMA films.
Packed in 1kg/bag, 25kg/drum
1. Tosyl azide is fatal if swallowed and highly flammable, with solutions typically containing a large proportion of toluene, which presents additional health and environmental hazards.
2. Tosyl azide is suspected of damaging fertility or the unborn child and may cause organ damage through prolonged or repeated exposure.
3. Wear full protective equipment (chemical-resistant gloves, protective clothing, eye/face protection) and work in a fume hood. In case of contact with water or incompatible materials, toxic gases may be released.
1. Immediately eliminate all ignition sources, isolate the area, and ensure adequate ventilation. Wear full personal protective equipment, including a self-contained breathing apparatus if necessary.
2. Cover the spill with an inert, liquid-absorbent material and carefully collect it into a sealed, properly labeled container for disposal. Do not allow the material to dry out.
3. Prevent the material from entering drains or waterways, as it is toxic to aquatic life. Dispose of all collected waste in accordance with local environmental regulations.
1. Store Tosyl azide in a tightly sealed container at 2-8°C in a cool, well-ventilated area, away from heat, sparks, and open flames.
2. Keep Tosyl azide away from strong oxidizing agents and sources of ignition, and ensure proper grounding and bonding of equipment to prevent static discharge.
3. Handle Tosyl azide with extreme care as it is a potential explosive, especially when dry or heated above 100°C; it is often supplied as a solution (e.g., in toluene) to mitigate these risks.
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