Tris(2-methoxyphenyl)phosphine CAS 4731-65-1
Product Name: Tris(2-Methoxyphenyl)phosphine
CAS: 4731-65-1
MF: C21H21O3P
MW: 352.36
EINECS: 225-235-8
Melting point: 204-208 °C
Boiling point: 477.3±40.0 °C(Predicted)
Storage temp.: Inert atmosphere,Room Temperature
1. Tris(2-Methoxyphenyl)phosphine CAS 4731-65-1 is commonly used as an electron-rich, sterically hindered ligand in transition metal catalysis, especially for palladium-catalyzed cross-coupling reactions (e.g., Suzuki-Miyaura). Its 2-methoxyphenyl groups boost electron density on the phosphine center while providing spatial bulk, enhancing catalytic activity for sterically demanding substrates.
2. Tris(2-Methoxyphenyl)phosphine serves as a precursor in organophosphorus chemistry—it reacts with electrophiles (e.g., alkyl halides, acid chlorides) to form functionalized phosphine derivatives, which are key for developing tailored ligands in fine chemical and pharmaceutical synthesis.
3. Tris(2-Methoxyphenyl)phosphine CAS 4731-65-1 is used in coordination chemistry to stabilize low-valent metal complexes (e.g., with nickel or platinum); its three 2-methoxyphenyl substituents balance solubility and steric protection, supporting the preparation of reactive intermediates for industrial-scale chemical processes.
Packed in 25 kg per drum or based on customers' requirements.
1. Store Tris(2-Methoxyphenyl)phosphine CAS 4731-65-1 in a tightly sealed, airtight container (preferably amber glass) under an inert gas (e.g., nitrogen or argon) to shield its phosphine group from air oxidation, which would reduce its efficacy as an electron-rich catalysis ligand.
2. Keep Tris(2-Methoxyphenyl)phosphine in a cool, dry, dark area away from direct sunlight and heat sources; light and elevated temperatures can accelerate decomposition, compromising its stability for organophosphorus synthesis and metal complex preparation.
3. Avoid storing Tris(2-Methoxyphenyl)phosphine CAS 4731-65-1 near strong oxidizing agents (e.g., peroxides, nitric acid) or moisture—these can trigger unwanted reactions with its phosphine or methoxy moieties, ensuring the compound remains viable for cross-coupling and industrial chemical processes.
